A slide from a presentation on the results of a study. It has a blue background and white text. The slide is divided into three sections. The first section is titled "Conclusions" and it explains that patients with RMRMS or CIS randomized to ifni-1b or GA and image monthly for up to 2 years showed 3 distinct patterns of brain activity (CAL) - no new CAL waves of CAL frequent CAL and frequency CAL. The second section explains that we found no differences in CAL patterns between the 2 treatment groups. The third section discusses CAL patterns significantly correlated with worsening function as measured both by ed's or the MSFC. The fourth section discusses patients with frequent CAL showed lower cognitive function which was apparent already at study entry.

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