A diagram that shows the molecular activity of tolerance and sensitization. It is a cross-section of a protein molecule which is represented by a blue circle.
The molecule is divided into two parts. The top part of the molecule is labeled "Molecular Activity of Tolerance and Sensitization" and has a label that reads "Opioid Agonists". The label also mentions that the molecule contains an opioid receptor a second messenger and a protein kinase.
There are also several other components in the molecule including a gene transcription factor (CREB AFOSB) and a pain perception factor (Pain Perception). These components are responsible for the transcription factor of the gene transcription which helps to regulate the expression of pain in the body. The image also shows the interaction between the two components which can be seen in the top right corner of the image.
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Date
2011
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Date
2005
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Date
2010
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