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This is a run chart with Time (from 0 to 12 hours) on the x-axis and Plasma hydrocodone concentration (in mg/mL) on the y-axis. The data shows that Single Dose (Period 1) takes 7 hours to build from 0 mg/mL to 28 mg/ML which it holds for hours 7-12. The data also shows that Steady State (Period 2) takes 3 hours to build from 52 mg/mL to 60 mg/ML which it holds for hours 3-6 before steadily declining (to 45 mg/mL at hour 12).

Title

Mean (SD) plasma hydrocodone concentration vs time profiles through 12 hours after administration of a 45-mg dose

Description

This is a run chart with Time (from 0 to 12 hours) on the x-axis and Plasma hydrocodone concentration (in mg/mL) on the y-axis. The data shows that Single Dose (Period 1) takes 7 hours to build from 0 mg/mL to 28 mg/ML which it holds for hours 7-12. The data also shows that Steady State (Period 2) takes 3 hours to build from 52 mg/mL to 60 mg/ML which it holds for hours 3-6 before steadily declining (to 45 mg/mL at hour 12).

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