An illustration of a man in a green suit standing next to a green car with the hood open. The man appears to be in distress with his head in his hands and a concerned expression on his face. The car is engulfed in flames and smoke and there are other people in the background. The text on the image reads "Magnesium (oxycodone HCI/acetaminophen) for relief of moderate to moderately severe pain. Two-tablet dosing stays under the acetaminophen threshold. High daily doses of acetaminophen have the potential to result in hepatotoxicity. Safety considerations. The most frequently observed adverse reactions with magnesium tablets include light-headedness dizziness sedation nausea and vomiting. Patients should be monitored for signs and symptoms of oxycodone overdose such as respiratory depression."
 
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                        ![A screenshot from the Exalgo website. It appears to show case studies for how to convert different example patients to Exalgo step-by-step. The website is of example patient Dennis and the "Dose Conversion" step is selected. The website has a blue and white color scheme with a blue header and black footer.<br /><br />The main text of the page reads "Exalgo could give Dennis the pain relief he wants - with a once-daily dose. Double-blind placebo-controlled withdrawal study of opioid-tolerant patients with low back pain (447 enrolled 268 randomized; 66[49%] EXALGO patients and 44 [31%) placebo patients completed the study". Below that there is additional text that reads "Conversion/Titration Phase: EXALGO reduced mean pain intensity (NRS*) by 50% in successfully converted patients". <br /><br />The bottom of the page also has indication and important risk information. In the lower right corner there is an image of a person walking a dog on a leash with a tree in the background. The footer has the Exalgo logo and a navigation menu.](https://oida-resources-images.azureedge.net/public/full/788d6c94-1a49-4186-9b61-4e458d11f420.png) 
                         
                         
                         
                         
                         
                         
                         
                         
                         
                         
                         
                         
                         
                        