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A bar graph titled "Percentage of patients discontinuing due to treatment-emergent adverse events". The x-axis of the graph is labeled "Osteoarthritis Study (12 weeks) N = 1023". The y-axis is labeled "Percentage of patients" with a range of values from 0 to 50. The bars on the graph represent NUCYNTA ER 100 to 250 mg bid (19%) Oxycodone CR 20 to 50 mg bid (43%) and placebo (7%). Text at the bottom of the image reads: "Clinical trials conducted with controlled-release oxycodone which is the active ingredient in OxyContin®. OxyContin® is a registered trademark of Purdue Pharma Inc."

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A bar graph titled "Percentage of patients discontinuing due to treatment-emergent adverse events". The x-axis of the graph is labeled "Osteoarthritis Study (12 weeks) N = 1023". The y-axis is labeled "Percentage of patients" with a range of values from 0 to 50. The bars on the graph represent NUCYNTA ER 100 to 250 mg bid (19%) Oxycodone CR 20 to 50 mg bid (43%) and placebo (7%). Text at the bottom of the image reads: "Clinical trials conducted with controlled-release oxycodone which is the active ingredient in OxyContin®. OxyContin® is a registered trademark of Purdue Pharma Inc."

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"A bar graph titled "Percentage of patients discontinuing due to treatment-emergent adverse events". The x-axis of the graph is labeled &quo...