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A screenshot of a webpage from the NUCYNTA ER website. The webpage is titled "Tolerability profile" and has a red and white color scheme. <br /><br />On the left side of the page there is a table with three columns and three rows. The first column is labeled "In a clinical study in chronic pain due to osteoarthritis of the knee" and the second column is titled as "Low discontinuation rate due to AES". The third column has a bar graph that shows the percentage of patients who have been diagnosed with the disease. The graph is divided into three sections - G1 G2 and G3.<br /><br />The first section of the webpage has a list of different types of tolerability profiles each with a different color bar representing a different type of tolerance profile. The bars are color-coded with the highest percentage being red the lowest being green and the smallest being yellow. The text on the page explains that the profile is related to low discontinuation rates due to the AES which are 19% of the patients who are diagnosed with NUCYNTA ER. There is also a section titled "Selected Important Safety Information" which provides information about the safety information available on the website.<br />- There is a button at the bottom right corner that says "Click here for more comprehensive safety information."

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A screenshot of a webpage from the NUCYNTA ER website. The webpage is titled "Tolerability profile" and has a red and white color scheme.

On the left side of the page there is a table with three columns and three rows. The first column is labeled "In a clinical study in chronic pain due to osteoarthritis of the knee" and the second column is titled as "Low discontinuation rate due to AES". The third column has a bar graph that shows the percentage of patients who have been diagnosed with the disease. The graph is divided into three sections - G1 G2 and G3.

The first section of the webpage has a list of different types of tolerability profiles each with a different color bar representing a different type of tolerance profile. The bars are color-coded with the highest percentage being red the lowest being green and the smallest being yellow. The text on the page explains that the profile is related to low discontinuation rates due to the AES which are 19% of the patients who are diagnosed with NUCYNTA ER. There is also a section titled "Selected Important Safety Information" which provides information about the safety information available on the website.
- There is a button at the bottom right corner that says "Click here for more comprehensive safety information."

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"A screenshot of a webpage from the NUCYNTA ER website. The webpage is titled "Tolerability profile" and has a red and white color scheme. <...