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A slide from a presentation titled "History of fentanyl". Below the title there is a timeline from 1968 to 2012. The dates from 1998 to 2012 are highlighted and labeled "Transmucosal Immediate-Release fentanyl (TIRF)". Each date has a small icon representing the product that was introduced in that year. Text at the bottom of the page reads: "More rapid onset more closely matches timing of breakthrough pain. IV doses for anesthesia are higher than those used for pain."

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A slide from a presentation titled "History of fentanyl". Below the title there is a timeline from 1968 to 2012. The dates from 1998 to 2012 are highlighted and labeled "Transmucosal Immediate-Release fentanyl (TIRF)". Each date has a small icon representing the product that was introduced in that year. Text at the bottom of the page reads: "More rapid onset more closely matches timing of breakthrough pain. IV doses for anesthesia are higher than those used for pain."

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"A slide from a presentation titled "History of fentanyl". Below the title there is a timeline from 1968 to 2012. The dates from 1998 to 201...