An advertisement for Dennis a medication company. It features a black and white illustration of Dennis holding a dog in his arms. Dennis is wearing a suit and tie and has a serious expression on his face. The background is orange and there is text on the left side of the image that reads "Dennis: Medication history: Hydrocodone with acetaminophen 5 mg/500 mg every 4 to 6 hours PRN for pain. Inadequate pain relief after 6 months despite dose escalations. Switched to Kadian® (morphine ER) 30 mg/day. Patient experienced nausea constipation. Switched to OxyContin® (oxycodone ER) tablets 30 mg BID increased 2 weeks ago. Patient complains of inadequate pain relief worsening constipation and drowsiness." On the right side there is a logo for Exalgo a company that provides information about Dennis's medication history.
Description 
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Category
Source 1 of 4
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Date
2010
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Date
2010
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Date
2010
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2010
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![An advertisement for Nucynta ER with sections for "Discontinuation Rates Due to Adverse Events" and "Incidence of Opioid Withdrawal Symptoms". There is also a bar graph with the title "Incidence of treatment-emergent adverse events leading to discontinuation reported by [greater than or equal-to] 2% of patients". The background is white and red with text in red black and white.<br /><br />On the right side there is "Selected Important Safety Information". The logo of logo of Nucynta ER is at the bottom.](https://oida-resources-images.azureedge.net/public/full/38ba2066-6f55-47b4-9093-78b9be045673.jpg)
